MCAM anticorps (AA 600-650)

N° du produit ABIN7450088

L’anticorps Lapin Polyclonal anti-MCAM a été validé pour WB et IP. Il convient pour détecter MCAM dans des échantillons de Humain et Souris.

Aperçu rapide pour MCAM anticorps (AA 600-650) (ABIN7450088)

Antigène: MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCAM est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-MCAM anticorps

Épitope: AA 600-650

Fonction: Rabbit anti-CD146 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 600 and 650

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur MCAM

Antigène: MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Autre désignation: CD146

Sujet: Background: CD146 plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. CD146 could be an adhesion molecule active in neural crest cells during embryonic development. CD146 acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration [taken from the Universal Protein Resource (UniProt) P43121].

ID gène: 4162

NCBI Accession: NP_006491

UniProt: P43121