CDK1 anticorps (AA 225-275)

N° du produit ABIN7450100

L’anticorps Lapin Polyclonal anti-CDK1 a été validé pour WB et IP. Il convient pour détecter CDK1 dans des échantillons de Humain.

Aperçu rapide pour CDK1 anticorps (AA 225-275) (ABIN7450100)

Antigène: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-CDK1 anticorps

Épitope: AA 225-275

Fonction: Rabbit anti-CDK1 Antibody, Affinity Purified

Homologie: Mouse,Rat,Bovine,Orangutan

Purification: Affinity Purified

Immunogène: Between AA 225 and 275

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur CDK1

Antigène: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Autre désignation: CDK1

Sujet: Background: Cyclin-dependent kinase 1 (CDK1) is a member of the Ser/Thr protein kinase family. CDK1 is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of CKD1 is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control [taken from NCBI Entrez Gene (Gene ID: 983)].

ID gène: 983

NCBI Accession: NP_001777

UniProt: P06493

Pathways: Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA