HRS (HRS) (C-Term) anticorps

N° du produit ABIN7450342

Détail du produit

Antigène: HRS

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunoprecipitation (IP)

Fonction: Rabbit anti-HRS Antibody, Affinity Purified

Homologie: Bovine

Purification: Affinity Purified

Immunogène: between AA 727 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détail du antigène

Antigène: HRS

Autre désignation: HRS (HRS Produits)

Synonymes: anticorps HRS, anticorps Hrs, anticorps Hgr, anticorps ZFYVE8, anticorps hepatocyte growth factor-regulated tyrosine kinase substrate, anticorps hepatoCyte growth factor receptor, anticorps HGF-regulated tyrosine kinase substrate, anticorps HGS, anticorps Hgs, anticorps Tsp_05936

Sujet: Background: Hepatocyte growth factor-regulated tyrosine kinase substrate (HRS) is an endosomal protein that participates in the trafficking and sorting of proteins to degradative or recycling pathways. HRS can bind ubiquitin directly and plays a key role in sorting ubiquitinated proteins to lysosomes. HRS has also been demonstrated to regulate protein sorting independent of its ubiquitin-binding motif.

ID gène: 9146

NCBI Accession: NP_004703

UniProt: O14964

Pathways: CXCR4-mediated Signaling Events, EGFR Downregulation