HRS (HRS) (AA 3-777) anticorps

N° du produit ABIN7873553

Cet anticorps Souris Monoclonal détecte spécifiquement HRS dans WB, FACS et IHC (p). Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour HRS (HRS) (AA 3-777) anticorps (ABIN7873553)

Antigène: HRS

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 6C2E1

Détail du produit

Épitope: AA 3-777

Fonction: HRS Antibody / HGS / HGF-regulated tyrosine kinase substrate

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids R3-D777) was used as the immunogen for the HRS antibody.

Isotype: IgG1

Information d'application

Indications d'application: Optimal dilution of the HRS antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the HRS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détail du antigène

Antigène: HRS

Autre désignation: HRS

Sujet: Hepatocyte growth factor-regulated tyrosine kinase substrate is an enzyme that in humans is encoded by the HGS gene. It is mapped to 17q25.3. The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation.

UniProt: O14964

Pathways: CXCR4-mediated Signaling Events, EGFR Downregulation