PAK4 anticorps (AA 25-75)

N° du produit ABIN7450536

Cet anticorps anti-PAK4 est un anticorps Lapin Polyclonal détectant PAK4 dans WB et IP. Adapté pour Humain et Souris.

Aperçu rapide pour PAK4 anticorps (AA 25-75) (ABIN7450536)

Antigène: PAK4 (P21-Activated Kinase 4 (PAK4))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAK4 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-PAK4 anticorps

Épitope: AA 25-75

Fonction: Rabbit anti-PAK4 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 25 and 75

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Phosphate Buffered Saline (PBS) containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PAK4

Antigène: PAK4 (P21-Activated Kinase 4 (PAK4))

Autre désignation: PAK4

Sujet: Background: PAK4 is a member of the PAK family of serine/threonine p21-activating kinases. PAK4 is a target for the GTP-bound Rho GTPase, CDC42, and is an important factor that links Rho GTPases such as Ras to transformation. In this context, PAK4 is highly transforming, and has been found to be highly expressed in some tumor cell lines. PAK4 has been demonstrated to activate the JNK pathway and mediate the formation of filopodia and the reorganization of the actin cytoskeleton. PAK4 has also been found to function as a regulator of prosurvival pathways and senescence.

ID gène: 10298

NCBI Accession: NP_005875

UniProt: O96013

Pathways: Signalisation RTK