WNK1 anticorps (AA 2100-2150)

N° du produit ABIN7450908

Cet anticorps anti-WNK1 est un anticorps Lapin Polyclonal détectant WNK1 dans WB et IP. Adapté pour Humain et Souris.

Aperçu rapide pour WNK1 anticorps (AA 2100-2150) (ABIN7450908)

Antigène: WNK1 (WNK Lysine Deficient Protein Kinase 1 (WNK1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WNK1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-WNK1 anticorps

Épitope: AA 2100-2150

Fonction: Rabbit anti-WNK1 Antibody, Affinity Purified

Homologie: Rat

Purification: Affinity Purified

Immunogène: between AA 2100 and 2150

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur WNK1

Antigène: WNK1 (WNK Lysine Deficient Protein Kinase 1 (WNK1))

Autre désignation: WNK1

Sujet: Background: WNK1 (with no lysine 1) is a member of the WNK family of serine-threonine kinases. The WNK family of kinases has been observed to play a role in several cellular processes which include ion balance, signal transduction, survival, proliferation and organ development. WNK1 appears to be important to ion homeostasis. Mutations in WNK1 cause pseudohypoaldosteronism type II (PHA II), also called Gordon's syndrome, an autosomal dominant disease characterized by defects in ion transport in the nephron that result in hypertension and hyperkalemia. WNK1 has been reported to regulate sodium and chloride ion transport by influencing the activity of another WNK family member, WNK4. WNKF1 has also been observed to regulate ion homeostasis independent of WNK4.

ID gène: 65125

NCBI Accession: NP_061852

UniProt: Q9H4A3