Nicastrin anticorps (AA 659-709)
Aperçu rapide pour Nicastrin anticorps (AA 659-709) (ABIN7451011)
Antigène
Voir toutes Nicastrin (NCSTN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 659-709
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Fonction
- Rabbit anti-Nicastrin Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogène
- Between AA 659 and 709
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Isotype
- IgG
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Indications d'application
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IP: 2 - 10 μg/mg lysate
WB: 1:500 - 1:2,500
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Date de péremption
- 12 months
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- Nicastrin (NCSTN)
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Autre désignation
- Nicastrin
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Sujet
- Background: Nicastrin is an essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex [taken from the Universal Protein Resource (UniProt) Q92542].
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ID gène
- 23385
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NCBI Accession
- NP_056146
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UniProt
- Q92542
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Pathways
- Signalisation Notch, Neurotrophin Signaling Pathway
Antigène
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