PITRM1 anticorps (AA 987-1037)

N° du produit ABIN7451174

L’anticorps Lapin Polyclonal anti-PITRM1 a été validé pour IP. Il convient pour détecter PITRM1 dans des échantillons de Humain.

Aperçu rapide pour PITRM1 anticorps (AA 987-1037) (ABIN7451174)

Antigène: PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PITRM1 est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-PITRM1 anticorps

Épitope: AA 987-1037

Fonction: Rabbit anti-PITRM1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 987 and 1037

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. ABIN7451174 has not performed satisfactorily when used for WB of PITRM1 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of PITRM1.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PITRM1

Antigène: PITRM1 (Pitrilysin Metallopeptidase 1 (PITRM1))

Autre désignation: PITRM1

Sujet: Background: Pitrilysin metalloproteinase 1 (PITRM1) is an ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. PITRM1 also degrades other unstructured peptides. It is specific for peptides in the range of 10 to 65 residues. It is able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. PTMRM shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference [taken from the Universal Protein Resource (UniProt) Q5JRX3].

ID gène: 10531

UniProt: Q5JRX3

Pathways: Signalisation PI3K-Akt, SARS-CoV-2 Protein Interactome