Cyclin A anticorps (AA 382-432)

N° du produit ABIN7451206

Cet anticorps Lapin Polyclonal détecte spécifiquement Cyclin A dans IP. Il présente une réactivité envers Humain.

Aperçu rapide pour Cyclin A anticorps (AA 382-432) (ABIN7451206)

Antigène: Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin A est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-Cyclin A anticorps

Épitope: AA 382-432

Fonction: Rabbit anti-CCNA2/Cyclin A2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 382 and 432

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-CCNA2/Cyclin A2 antibody ABIN7450082.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Cyclin A

Antigène: Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

Autre désignation: CCNA2/Cyclin A2

Sujet: Background: The protein encoded by the gene CCNA2, Cyclin A2, belongs to the highly conserved cyclin family. Members of the cyclin family are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, Cyclin A2 is expressed in all tissues tested. Cyclin A2 binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions [taken from NCBI Entrez Gene ID: 890].

ID gène: 890

UniProt: P20248

Pathways: Signalisation PI3K-Akt, Cycle Cellulaire, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA