SETMAR anticorps (AA 225-275)

N° du produit ABIN7451473

Cet anticorps Lapin Polyclonal détecte spécifiquement SETMAR dans IP. Il présente une réactivité envers Humain.

Aperçu rapide pour SETMAR anticorps (AA 225-275) (ABIN7451473)

Antigène: SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SETMAR est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-SETMAR anticorps

Épitope: AA 225-275

Fonction: Rabbit anti-Metnase Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: Between AA 225 and 275

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 10 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur SETMAR

Antigène: SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))

Autre désignation: Metnase

Sujet: Background: Metnase is also known as Histone-lysine N-methyltransferase SETMAR. Metnase is a histone methyltransferase that methylates 'Lys-4' and 'Lys-36' of histone H3, 2 specific tags for epigenetic transcriptional activation. Metanase specifically mediates dimethylation of H3 'Lys-36', and has sequence-specific DNA-binding activity and recognizes the 19-mer core of the 5'-terminal inverted repeats (TIRs) of the Hsmar1 element. Metnase possessess DNA nicking activity and in vivo end joining activity, and it may mediate genomic integration of foreign DNA [taken from the Universal Protein Resource (UniProt) Q53H47].

ID gène: 6419

UniProt: Q53H47

Pathways: Positive Regulation of Response to DNA Damage Stimulus