AKAP8 anticorps (AA 575-625)

N° du produit ABIN7451616

Cet anticorps anti-AKAP8 est un anticorps Lapin Polyclonal détectant AKAP8 dans WB et IP. Adapté pour Humain.

Aperçu rapide pour AKAP8 anticorps (AA 575-625) (ABIN7451616)

Antigène: AKAP8 (A Kinase (PRKA) Anchor Protein 8 (AKAP8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKAP8 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-AKAP8 anticorps

Épitope: AA 575-625

Fonction: Rabbit anti-AKAP8/AKAP95 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 575 and 625

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur AKAP8

Antigène: AKAP8 (A Kinase (PRKA) Anchor Protein 8 (AKAP8))

Autre désignation: AKAP8/AKAP95

Sujet: Background: AKAP8/AKAP95 has been characterized as a 95 kDa protein kinase A (PKA)-anchoring protein and regulatory subunit of PKA that functions to recruit the condensin complex for chromosome condensation during mitosis. A role in DNA replication has also been demonstrated through its interaction with the pre-replication complex component, MCM2 (mini-chromosome maintenance 2). Inhibition of AKAP8/AKAP95 association with MCM2 inhibits replication initiation and elongation in vitro. AKAP8/AKAP95 has also been shown to be involved in apoptosis. KAP8/AKAP95 associates with caspase 3 and serves as a carrier to transport caspase 3 from the cytoplasm to the nucleus to induce morphological changes in the nucleus.

ID gène: 10270

NCBI Accession: NP_005849

UniProt: O43823

Pathways: SARS-CoV-2 Protein Interactome