Tuberin anticorps (C-Term)

N° du produit ABIN7452209

L’anticorps Lapin Polyclonal anti-Tuberin a été validé pour WB et IP. Il convient pour détecter Tuberin dans des échantillons de Humain.

Aperçu rapide pour Tuberin anticorps (C-Term) (ABIN7452209)

Antigène: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tuberin est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-Tuberin anticorps

Épitope: C-Term

Fonction: Rabbit anti-TSC2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 1750 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: 1:5,000 - 1:15,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Tuberin

Antigène: Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Autre désignation: TSC2

Sujet: Background: Tuberous sclerosis 2 protein (TSC2) forms a heterodimer with TSC1 to integrate cellular growth and stress signals. Defects in the TSC1 and TSC2 gene are responsible for the genetic disorder tuberous sclerosis. The TSC1/TSC2 complex functions in the mTOR pathway by negatively regulating mTOR activity via the small GTP-binding protein Rheb. TSC2 also been shown to interact with FOXO1 transcription factor.

ID gène: 7249

NCBI Accession: NP_000539

UniProt: P49815

Pathways: Signalisation RTK, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus