CDKN1C anticorps (AA 266-316)

N° du produit ABIN7452239

L’anticorps anti-CDKN1C Polyclonal Lapin est utilisé pour la détection de CDKN1C dans des échantillons de Humain. Il a été validé pour IP.

Aperçu rapide pour CDKN1C anticorps (AA 266-316) (ABIN7452239)

Antigène: CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDKN1C est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-CDKN1C anticorps

Épitope: AA 266-316

Fonction: Rabbit anti-p57kip2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 266 and 316

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. ABIN7452239 has not performed satisfactorily when used for WB of p57KIP2 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of p57KIP2.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur CDKN1C

Antigène: CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

Autre désignation: p57kip2

Sujet: Background: p57kip2 is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate [taken from NCBI GeneID:1028].

ID gène: 1028

NCBI Accession: NP_000067

UniProt: P49918

Pathways: Cycle Cellulaire, Dopaminergic Neurogenesis