Acetyl-CoA Carboxylase alpha anticorps (AA 1925-1975)

N° du produit ABIN7452256

Cet anticorps Lapin Polyclonal détecte spécifiquement Acetyl-CoA Carboxylase alpha dans IP. Il présente une réactivité envers Humain.

Aperçu rapide pour Acetyl-CoA Carboxylase alpha anticorps (AA 1925-1975) (ABIN7452256)

Antigène: Acetyl-CoA Carboxylase alpha (ACACA)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Acetyl-CoA Carboxylase alpha est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-Acetyl-CoA Carboxylase alpha anticorps

Épitope: AA 1925-1975

Fonction: Rabbit anti-ACC1/ACC-alpha Antibody, Affinity Purified

Homologie: Mouse,Rat

Purification: Affinity Purified

Immunogène: between AA 1925 and 1975

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-ACC1/ACC-alpha antibody ABIN7452869.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Acetyl-CoA Carboxylase alpha

Antigène: Acetyl-CoA Carboxylase alpha (ACACA)

Autre désignation: ACC1/ACC-alpha

Sujet: Background: ACC1/ACC-alpha catalyzes the carboxylation of acetyl-CoA to malonyl-CoA in the enzymatic pathway of long-chain fatty-acid synthesis. ACC1/ACC-alpha has been identified as a partner of BRCA1. Through this interaction, ACC1/ACC-alpha may contribute to the tumor suppressor activity of BRCA1 as demonstrated by the finding that disruption of this interaction increases lipid synthesis in mammary epithelial cells. In this context, lipogenesis has been closely linked to tumorigenesis and ACC1/ACC-alpha has been found to be highly expressed in human breast carcinomas.

ID gène: 31

NCBI Accession: NP_942131

UniProt: Q13085

Pathways: AMPK Signaling, Ribonucleoside Biosynthetic Process, L'effet Warburg