UBR1 anticorps (AA 225-275)

N° du produit ABIN7452547

Cet anticorps Lapin Polyclonal détecte spécifiquement UBR1 dans IP. Il présente une réactivité envers Humain.

Aperçu rapide pour UBR1 anticorps (AA 225-275) (ABIN7452547)

Antigène: UBR1 (Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBR1 est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-UBR1 anticorps

Épitope: AA 225-275

Fonction: Rabbit anti-UBR1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 225 and 275

Isotype: IgG

Information d'application

Indications d'application:

IP: 2 - 5 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur UBR1

Antigène: UBR1 (Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1))

Autre désignation: UBR1

Sujet: Background: UBR1 is an E3 ubiquitin-protein ligase that is a component of the N-end rule pathway. UBR1 recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. UBR1 may be involved in pancreatic homeostasis. UBR1 binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth [taken from the Universal Protein Resource (UniProt) Q8IWV7].

ID gène: 197131

NCBI Accession: NP_777576

UniProt: Q8IWV7