Recombinant TWIST1 anticorps (AA 1-50)

N° du produit ABIN7453340

L’anticorps Lapin Monoclonal anti-TWIST1 a été validé pour WB, IP et ICC. Il convient pour détecter TWIST1 dans des échantillons de Humain.

Aperçu rapide pour Recombinant TWIST1 anticorps (AA 1-50) (ABIN7453340)

Antigène: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TWIST1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: BLR156J

Détail du produit anti-TWIST1 anticorps

Épitope: AA 1-50

Fonction: Rabbit anti-TWIST Recombinant Monoclonal Antibody [BLR156J]

Immunogène: between AA 1 and 50

Isotype: IgG

Information d'application

Indications d'application:

IP: 20 μL/1 mg lysate

ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

WB: 01:01,00

Restrictions: For Research Use only

Stockage

Concentration: 250 μg/mL

Buffer: Phosphate Buffered Saline (PBS) containing 0.2 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur TWIST1

Antigène: TWIST1 (Twist Homolog 1 (Drosophila) (TWIST1))

Autre désignation: TWIST1

Sujet: Background: TWIST1 is a basic helix-loop-helix (bHLH) transcription factor that plays an important role in embryonic development. TWIST1 forms both homodimers and heterodimers that bind to DNA E box sequences and regulate the transcription of genes involved in cranial suture closure during skull development. TWIST1 may also regulate neural tube closure, limb development and brown fat metabolism. The TWIST1 gene is hypermethylated and overexpressed in multiple human cancers, and the encoded protein promotes tumor cell invasion and metastasis, as well as metastatic recurrence. [taken from NCBI Entrez Gene (Gene ID: 7291)].

ID gène: 7291

NCBI Accession: NP_000465

UniProt: Q15672

Pathways: Signalisation p53, Proton Transport, Tube Formation, Negative Regulation of Transporter Activity