PRKDC anticorps (AA 2100-2150)

N° du produit ABIN7453820

L’anticorps Lapin Polyclonal anti-PRKDC a été validé pour WB, IP et IHC (fp). Il convient pour détecter PRKDC dans des échantillons de Humain.

Aperçu rapide pour PRKDC anticorps (AA 2100-2150) (ABIN7453820)

Antigène: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKDC est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-PRKDC anticorps

Épitope: AA 2100-2150

Fonction: Rabbit anti-DNA-PKcs Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 2100 and 2150

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: ABIN7453820 is less efficient than ABIN7451557, ABIN7449674 or ABIN7451558.

WB: 1:1,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PRKDC

Antigène: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Autre désignation: DNA-PKcs

Sujet: Background: DNA-PKcs is the catalytic subunit of a DNA-dependent serine-threonine protein kinase (DNA-PK). DNA-PK is a heterotrimer comprised of DNA-PKcs and the Ku709/Ku86 dimer. DNA-PK is involved in DNA damage repair and V(D)J recombination. DNA-PK phosphorylates Artemis, a protein required for nonhomologous end-joining and is necessary for the loading of Artemis on damaged DNA.

ID gène: 5591

NCBI Accession: NP_008835

UniProt: P78527

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response