Prohibitin anticorps (AA 222-272)

N° du produit ABIN7453838

L’anticorps Lapin Polyclonal anti-Prohibitin a été validé pour WB, IHC (fp) et IP. Il convient pour détecter Prohibitin dans des échantillons de Humain.

Aperçu rapide pour Prohibitin anticorps (AA 222-272) (ABIN7453838)

Antigène: Prohibitin (PHB)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Prohibitin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunoprecipitation (IP)

Détail du produit anti-Prohibitin anticorps

Épitope: AA 222-272

Fonction: Rabbit anti-Prohibitin Antibody, Affinity Purified

Homologie: Mouse,Rat,Bovine

Purification: Affinity Purified

Immunogène: between AA 222 and 272

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Prohibitin

Antigène: Prohibitin (PHB)

Autre désignation: Prohibitin

Sujet: Background: Prohibitin (PHB) has been identified as a tumor suppressor protein that can repress E2F-mediated transcription and arrest cell cycle progression. It has recently been shown to associate with members of the minichromosome maintenance complex such as MCM2, MCM5, and MCM7 and therefore is thought to impart its growth inhibitory effects via association with the replication machinery. Prohibitin is also implicated in regulating mitochondrial respiration and playing a role in aging.

ID gène: 5245

NCBI Accession: NP_002625

UniProt: P35232

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling