BAF53A anticorps (AA 25-75)

N° du produit ABIN7453898

L’anticorps Lapin Polyclonal anti-BAF53A a été validé pour WB et IHC (fp). Il convient pour détecter BAF53A dans des échantillons de Humain et Souris.

Aperçu rapide pour BAF53A anticorps (AA 25-75) (ABIN7453898)

Antigène: BAF53A (Actin-Like 6A (BAF53A))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAF53A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-BAF53A anticorps

Épitope: AA 25-75

Fonction: Rabbit anti-BAF53A Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 25 and 75

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur BAF53A

Antigène: BAF53A (Actin-Like 6A (BAF53A))

Autre désignation: BAF53A

Sujet: Background: BAF53A is a 53kd subunit of the BAF (BRG1/brm-associated factor) complex, a SWI/SNF chromatin remodeling and histone acetyltransferase complex that functions in the regulation of gene transcription. In the BAF complex, BAF53A is important to the ATPase activity of SMARCA4/BRG1 and the association of the BAF complex with chromatin. BAF53A also appears to be important to the formation of higher-order chromatin structure and has been shown to associate with mitotic chromosomes. Recently, BAF53A has been found to interact with p53 and repress p53-mediated gene transcription in a BRG1-independent manner.

ID gène: 86

NCBI Accession: NP_004292

UniProt: O96019

Pathways: Chromatin Binding, Photoperiodism