KDM4A anticorps (AA 350-400)

N° du produit ABIN7454377

L’anticorps Lapin Polyclonal anti-KDM4A a été validé pour IP et IHC (fp). Il convient pour détecter KDM4A dans des échantillons de Humain.

Aperçu rapide pour KDM4A anticorps (AA 350-400) (ABIN7454377)

Antigène: KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM4A est non-conjugé

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-KDM4A anticorps

Épitope: AA 350-400

Fonction: Rabbit anti-JMJD2A Antibody, Affinity Purified

Homologie: Orangutan

Purification: Affinity Purified

Immunogène: between AA 350 and 400

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-JMJD2A antibody A300-861A.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur KDM4A

Antigène: KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

Autre désignation: JMJD2A

Sujet: Background: JMJD2A is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. JMJD2A is a trimethylation-specific demethylase and functions as a transcriptional repressor. JMJD2A interacts with pRb and class one histone deacetylases to mediate repression of E2F-regulated promoters.

ID gène: 9682

NCBI Accession: NP_055478

UniProt: O75164

Pathways: L'effet Warburg