TFAM anticorps (AA 146-196)

N° du produit ABIN7454483

Cet anticorps anti-TFAM est un anticorps Lapin Polyclonal détectant TFAM dans IP et IHC (fp). Adapté pour Humain.

Aperçu rapide pour TFAM anticorps (AA 146-196) (ABIN7454483)

Antigène: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TFAM est non-conjugé

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-TFAM anticorps

Épitope: AA 146-196

Fonction: Rabbit anti-TFAM Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 146 and 196

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur TFAM

Antigène: TFAM (Transcription Factor A, Mitochondrial (TFAM))

Autre désignation: TFAM

Sujet: Background: Transcription factor A, mitochondrial (TFAM) binds to the mitochondrial light strand promoter and functions in mitochondrial transcriptional regulation. TFAM is required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase and promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. TFMA is required for maintenance of normal levels of mitochondrial DNA and may play a role in organizing and compacting mitochondrial DNA [taken from the Universal Protein Resource (UniProt) Q00059].

ID gène: 7019

NCBI Accession: NP_003192

UniProt: Q00059

Pathways: Chromatin Binding