JUP anticorps (AA 695-745)

N° du produit ABIN7454953

L’anticorps Lapin Polyclonal anti-JUP a été validé pour WB, IP et IHC (fp). Il convient pour détecter JUP dans des échantillons de Humain.

Aperçu rapide pour JUP anticorps (AA 695-745) (ABIN7454953)

Antigène: JUP (Junction Plakoglobin (JUP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JUP est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-JUP anticorps

Épitope: AA 695-745

Fonction: Rabbit anti-Plakoglobin Antibody, Affinity Purified

Homologie: Mouse

Purification: Affinity Purified

Immunogène: Between AA 695 and 745

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur JUP

Antigène: JUP (Junction Plakoglobin (JUP))

Autre désignation: Plakoglobin

Sujet: Background: Plakoglobin (gamma-catenin) is a member of the catenin family of proteins. It bears an armadillo repeat motif and plays a role in cell signaling, but unlike beta-catenenin, which plays a major role in the Wnt signaling pathway, plakoglobin is thought to act as a tumor/metastasis suppressor. Plakoglobin also functions as a junctional plaque protein and forms complexes with cadherins and desmosomal cadherins.

ID gène: 3728

NCBI Accession: NP_002221

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location