MAVS anticorps (AA 150-200)

N° du produit ABIN7455082

L’anticorps Lapin Polyclonal anti-MAVS a été validé pour WB, IP, ICC et IHC (fp). Il convient pour détecter MAVS dans des échantillons de Humain.

Aperçu rapide pour MAVS anticorps (AA 150-200) (ABIN7455082)

Antigène: MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAVS est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-MAVS anticorps

Épitope: AA 150-200

Fonction: Rabbit anti-MAVS/VISA Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 150 and 200

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 - 1:500. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

ICC: 1:100 - 1:500. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE cell sections.

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur MAVS

Antigène: MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))

Autre désignation: MAVS/VISA

Sujet: Background: Mitochondrial Antiviral-Signaling Protein (MAVS), also known as Virus-Induced Signaling Adaptor (VISA), is an adaptor protein that functions in the activation of the nuclear factor KappaB (NF-kappaB) and interferon regulatory factor 3 (IRF3) to mediate host innate immune responses against double-stranded RNA viral infection. MAVS (VISA) is localized to the outer mitochondrial membrane. Hepatitis C virus NS3/4A protease cleaves MAVS as part of an immune-evasion strategy.

ID gène: 57506

UniProt: Q7Z434

Pathways: Activation of Innate immune Response, Inositol Metabolic Process, Hepatitis C