Lamin A/C anticorps (AA 400-450)

N° du produit ABIN7455219

Cet anticorps Lapin Polyclonal détecte spécifiquement Lamin A/C dans WB, IP, IF/ICC et IHC (fp). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour Lamin A/C anticorps (AA 400-450) (ABIN7455219)

Antigène: Lamin A/C (LMNA)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Lamin A/C est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (fixed cells) (IF/ICC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-Lamin A/C anticorps

Épitope: AA 400-450

Fonction: Rabbit anti-Lamin-A Antibody, Affinity Purified

Homologie: Rat,Pig

Purification: Affinity Purified

Immunogène: between AA 400 and 450

Isotype: IgG

Information d'application

Indications d'application:

ICC-IF: 1:50 - 1:500. Formaldehyde fixation is recommended. Permeabilization with Triton-X 100 is recommended for formaldehyde-fixed cells.

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Lamin A/C

Antigène: Lamin A/C (LMNA)

Autre désignation: Lamin-A

Sujet: Background: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Lamin A/C plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics [taken from the Universal Protein Resource (UniProt) P02545].

ID gène: 4000

NCBI Accession: NP_733821

UniProt: P02545

Pathways: Apoptose, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus