IL21 Receptor anticorps

N° du produit ABIN7490532

Cet anticorps anti-IL21 Receptor est un anticorps Lapin Chimeric détectant IL21 Receptor dans ELISA et FACS. Adapté pour Humain.

Aperçu rapide pour IL21 Receptor anticorps (ABIN7490532)

Antigène: IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

Fragment: Fc fragment

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp IL21 Receptor est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Détail du produit anti-IL21 Receptor anticorps

Attributs du produit: Rabbit/Human Fc chimeric IgG1

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Information d'application

Indications d'application: ELISA 1:5000-10000, Flow Cyt  1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détails sur IL21 Receptor

Antigène: IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))

Autre désignation: IL21R

Sujet: CD360, IMD56, NILR,
Description: The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.

UniProt: Q9HBE5

Pathways: Signalistation JAK/STAT