CD35 anticorps (Biotin)

N° du produit ABIN7456648

L’anticorps anti-CD35 Monoclonal Souris est utilisé pour la détection de CD35 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour CD35 anticorps (Biotin) (ABIN7456648)

Antigène: CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD35 est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Clone: E11

Détail du produit anti-CD35 anticorps (Biotin)

Isotype: IgG1, kappa

Information d'application

Indications d'application: For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Commentaires:

Matching Isotype Control: Biotin Mouse Rat IgG1, κ Isotype Control (ABIN7469769)

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2~8°C. Do not freeze.

Détails sur CD35

Antigène: CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

Autre désignation: CD35

Sujet: Complement receptor type 1,CR1,C3b/C4b receptor,CD35,CR1,C3BR,CD35 is a type I single chain of glycoprotein, also known as C3b/C4b receptor, Complement Receptor type 1 or CR1. Four molecular weight allotypes (160kD, 190kD, 220kD, and 250kD) have been described. CD35 is expressed on granulocytes, monocytes, B cells, erythrocytes, and follicular dendritic cells, as well as subsets of NK and T cells. CD35 binds complement C3b, C4b, or iC3, and iC4, and plays important roles in both innate and adoptive immune response via mediating phagocytosis by granulocytes and monocytes. CD35 has also been reported to inhibit T-cell proliferation.

ID gène: 1378

UniProt: P17927

Pathways: Système du Complément, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity