CD80 anticorps

N° du produit ABIN7457845

L’anticorps Hamster arménien Monoclonal anti-CD80 a été validé pour FACS et BR. Il convient pour détecter CD80 dans des échantillons de Souris.

Aperçu rapide pour CD80 anticorps (ABIN7457845)

Antigène: CD80

Reactivité: Souris

Hôte: Hamster arménien

Clonalité: Monoclonal

Conjugué: Cet anticorp CD80 est non-conjugé

Application: Flow Cytometry (FACS), Blocking Reagent (BR)

Clone: 16-10A1

Détail du produit anti-CD80 anticorps

Purification: Purified

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Low Endotoxin: Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Matching Isotype Control: AF/LE Purified Armenian Hamster IgG Isotype Control (ABIN7469872)

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE)

Agent conservateur: Azide free

Stock: 4 °C

Stockage commentaire: Store at 2~8°C. Do not freeze.

Détails sur CD80

Antigène: CD80

Autre désignation: CD80

Sujet: T-lymphocyte activation antigen CD80,Cd80,Activation B7-1 antigen,B7,CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

ID gène: 12519

UniProt: Q00609

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints