Nibrin anticorps

N° du produit ABIN7464244

L’anticorps Souris Monoclonal anti-Nibrin a été validé pour WB, IF, ICC et IP. Il convient pour détecter Nibrin dans des échantillons de Humain.

Aperçu rapide pour Nibrin anticorps (ABIN7464244)

Antigène: Nibrin (NBN)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Nibrin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Classe de qualité: KO Validated

Clone: 1C3

Détail du produit anti-Nibrin anticorps

Réactivité croisée: Humain, Souris

Purification: Protein G purified

Immunogène: The complete coding region of the human p95/NBS1 expressed in E. coli.

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: 293T , MCF7 , HeLa , Raji

Validation: KO/KD, Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, No Preservative

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur Nibrin

Antigène: Nibrin (NBN)

Autre désignation: nibrin

Sujet: Nibrin , AT-V1 , AT-V2 , ATV , NBS , NBS1 , P95,Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]

Poids moléculaire: 85 kDa

ID gène: 4683

UniProt: O60934

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response