TET1 anticorps

N° du produit ABIN7464383

Cet anticorps anti-TET1 est un anticorps Souris Monoclonal détectant TET1 dans WB, IF et ICC. Adapté pour Humain.

Aperçu rapide pour TET1 anticorps (ABIN7464383)

Antigène: TET1 (Tet Methylcytosine Dioxygenase 1 (TET1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TET1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: GT465

Détail du produit anti-TET1 anticorps

Réactivité croisée: Humain

Purification: Affinity purified by Protein G.

Immunogène: Recombinant protein encompassing a sequence within the center region of human TET1. The exact sequence is proprietary.

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: DDDDK-human TET1-transfected 293T cells , NT2D1 nuclear extract

Validation: Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, No Preservative

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur TET1

Antigène: TET1 (Tet Methylcytosine Dioxygenase 1 (TET1))

Autre désignation: tet methylcytosine dioxygenase 1

Sujet: Tet methylcytosine dioxygenase 1 , CXXC6 , LCX , bA119F7.1,Dioxygenase that specifically binds methylcytosine (5mC), a minor base in mammalian DNA found in repetitive DNA elements that is crucial for retrotransposon silencing and mammalian development. Catalyzes the conversion of methylcytosine (5mC) to 5-hydroxymethylcytosine (hmC). The clear function of 5-hydroxymethylcytosine (hmC) is still unclear but it may influence chromatin structure and recruit specific factors or may constitute an intermediate component in cytosine demethylation. 5-hydroxymethylcytosine (hmC) is present in ES cells and is enriched in the brain, especially in Purkinje neurons. May play a role in the fetal development of heart, lung and brain.

Poids moléculaire: 235 kDa

ID gène: 80312

UniProt: Q8NFU7

Pathways: Stem Cell Maintenance, L'effet Warburg