Caspase 2 anticorps
Aperçu rapide pour Caspase 2 anticorps (ABIN7464666)
Antigène
Voir toutes Caspase 2 (CASP2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Réactivité croisée
- Humain
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Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human Caspase 2. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Commentaires
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Positive Control: Jurkat , Raji , NCI-H929 , HeLa
Validation: KO/KD
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
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Autre désignation
- caspase 2
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Sujet
- Caspase 2 , CASP-2 , ICH1 , NEDD-2 , NEDD2 , PPP1R57,This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq]
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Poids moléculaire
- 51 kDa
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ID gène
- 835
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UniProt
- P42575
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Pathways
- Apoptose, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway
Antigène
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