CBS anticorps

N° du produit ABIN7464920

Cet anticorps anti-CBS est un anticorps Souris Monoclonal détectant CBS dans WB et IHC (p). Adapté pour Humain.

Aperçu rapide pour CBS anticorps (ABIN7464920)

Antigène: CBS (Cystathionine-beta-Synthase (CBS))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CBS est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: KO Validated

Clone: GT519

Détail du produit anti-CBS anticorps

Réactivité croisée: Humain, Souris, Rat

Purification: Affinity purified by Protein G.

Immunogène: Recombinant protein encompassing a sequence within the center region of human CBS. The exact sequence is proprietary.

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: rat liver , Raji , K562 , mouse liver , 293T , HeLa , CBS-transfected 293T

Validation: KO/KD, Overexpression

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.97 mg/mL

Buffer: PBS, No Preservative

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur CBS

Antigène: CBS (Cystathionine-beta-Synthase (CBS))

Autre désignation: cystathionine-beta-synthase

Sujet: Cystathionine-beta-synthase , CBSL , HIP4,The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. [provided by RefSeq]

Poids moléculaire: 61 kDa

ID gène: 875

UniProt: P35520, P0DN79