Patched 1 anticorps (C-Term)

N° du produit ABIN7465681

L’anticorps Lapin Polyclonal anti-Patched 1 a été validé pour WB. Il convient pour détecter Patched 1 dans des échantillons de Humain.

Aperçu rapide pour Patched 1 anticorps (C-Term) (ABIN7465681)

Antigène: Patched 1 (PTCH1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Patched 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Patched 1 anticorps

Épitope: C-Term

Réactivité croisée: Humain

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PTCH1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: H1299

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.85 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur Patched 1

Antigène: Patched 1 (PTCH1)

Autre désignation: patched 1

Sujet: Patched 1 , BCNS , NBCCS , PTC , PTC1 , PTCH,This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently. [provided by RefSeq]

Poids moléculaire: 161 kDa

ID gène: 5727

UniProt: Q13635

Pathways: Signalisation Hedgehog, Carbohydrate Homeostasis, Tube Formation