ARHGEF18 anticorps

N° du produit ABIN7468884

Cet anticorps Souris Monoclonal détecte spécifiquement ARHGEF18 dans WB et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour ARHGEF18 anticorps (ABIN7468884)

Antigène: ARHGEF18 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ARHGEF18 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: GT1972

Détail du produit anti-ARHGEF18 anticorps

Réactivité croisée: Humain, Souris, Rat

Purification: Affinity purified by Protein G.

Immunogène: Recombinant protein encompassing a sequence within the center region of human ARHGEF18. The exact sequence is proprietary.

Isotype: IgG2a

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: Neuro2A , GL261 , C8D30 , NIH-3T3 , C2C12 , PC-12 , Rat-2 , 293T , A431 , HeLa , HepG2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, No Preservative

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur ARHGEF18

Antigène: ARHGEF18 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18))

Autre désignation: Rho/Rac guanine nucleotide exchange factor 18

Sujet:

Synonyms: Rho/Rac guanine nucleotide exchange factor 18 , P114-RhoGEF , RP78 , SA-RhoGEF , p114RhoGEF

Background: Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]

Poids moléculaire: 131 kDa

ID gène: 23370

UniProt: Q6ZSZ5

Pathways: Neurotrophin Signaling Pathway