TLE1 anticorps (N-Term)

N° du produit ABIN7469630

Cet anticorps anti-TLE1 Polyclonal Lapin (ABIN7469630) détecte spécifiquement TLE1 dans WB, IP et IHC (fro). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour TLE1 anticorps (N-Term) (ABIN7469630)

Antigène: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLE1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-TLE1 anticorps

Épitope: N-Term

Réactivité croisée: Humain, Souris

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human TLE1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-Fr: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: 293T , HepG2 Validation: KO/KD

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.31 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur TLE1

Antigène: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Autre désignation: TLE1

Sujet:

Synonyms: TLE family member 1, transcriptional corepressor , ESG , ESG1 , GRG1

Background: Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.

Poids moléculaire: 83 kDa

ID gène: 7088

UniProt: Q04724

Pathways: Signalisation WNT, SARS-CoV-2 Protein Interactome