LRRC4C anticorps (AA 561-640)

N° du produit ABIN720296

L’anticorps Lapin Polyclonal anti-LRRC4C a été validé pour WB, ELISA, IF (cc), IF (p), IHC (p) et IHC (fro). Il convient pour détecter LRRC4C dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour LRRC4C anticorps (AA 561-640) (ABIN720296)

Antigène: LRRC4C (Leucine Rich Repeat Containing 4C (LRRC4C))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRRC4C est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-LRRC4C anticorps

Épitope: AA 561-640

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Netrin G1 ligand

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur LRRC4C

Antigène: LRRC4C (Leucine Rich Repeat Containing 4C (LRRC4C))

Autre désignation: Netrin G1 ligand

Sujet:

Synonyms: Leucine rich repeat containing 4C, Leucine-rich repeat-containing protein 4C, LRC4C_HUMAN, Lrrc4C, Netrin-G1 ligand, NGL 1, NGL-1, NGL1.

Background: NGL-1 is a single pass type I membrane protein that acts as a cell adhesion molecule. It contains nine leucine-rich repeats (LRR) and one Ig-like C2-type domain. NGL-1 is predominantly expressed in the striatum and the cerebral cortex of both the embryonic and adult brain. NGL-1 specifically interacts with Netrin G1 (a molecule involved in axon guidance in the developing central nervous system) via its LRR region. NGL-1 plays a role in the regulation of neurite outgrowth of developing thalamic neurons. Soluble NGL-1 inhibits thalamic axon outgrowth while NGL-1 that is bound to the surface of developing thalamocortical axons stimulates growth. NGL-1 also interacts with Whirlin possibly stablizing interstereociliar links.

ID gène: 22854

Pathways: Synaptic Membrane