Recombinant CD47 anticorps

N° du produit ABIN7487701

Cet anticorps anti-CD47 est un anticorps Lapin Chimeric détectant CD47 dans IF et BP. Adapté pour Humain.

Aperçu rapide pour Recombinant CD47 anticorps (ABIN7487701)

Antigène: CD47

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp CD47 est non-conjugé

Application: Immunofluorescence (IF), Blocking Peptide (BP)

Clone: MIAP430

Détail du produit anti-CD47 anticorps

Fonction: Anti-CD47 [mIAP430], Rabbit IgG, kappa

Specificité: This antibody recognises CD47 which is a a multitransmembrane glycoprotein widely expressed on all hematopoietic cells and most other cell types. It is involved in cell adhesion, Ca2+ influx, platelet activation and peripheral mononuclear neutrophils migration across endothelial and epithelial monolayers.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG2a

Purification: Protein A affinity purified

Immunogène: This antibody was raised by immunising IAP-deficient mice with purified human placental CD47.

Isotype: IgG kappa

Information d'application

Indications d'application: This antibody can be used to investigate the role of the CD47 receptor. mIAP430 was first used to visualise the distribution of CD47 on fusing macrophages (Han et al., 2000). Further, it was demonstrated that this antibody can block fusion of macrophages by blocking CD47 and preventing the binding of this receptor with MFR (Han et al., 2000).

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur CD47

Antigène: CD47

Autre désignation: CD47

Sujet: IAP, C5/D5, Leukocyte surface antigen CD47, Antigenic surface determinant protein OA3, Integrin-associated protein, Protein MER6

UniProt: Q08722