GAB2 anticorps (AA 332-476)

N° du produit ABIN7539834

Cet anticorps Souris Monoclonal détecte spécifiquement GAB2 dans ELISA, IHC, FACS et ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour GAB2 anticorps (AA 332-476) (ABIN7539834)

Antigène: GAB2 (GRB2-Associated Binding Protein 2 (GAB2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GAB2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 1F6D9

Détail du produit anti-GAB2 anticorps

Épitope: AA 332-476

Fonction: GAB2 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human GAB2 (AA: 332-476) expressed in E. Coli.

Isotype: IgG2a

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur GAB2

Antigène: GAB2 (GRB2-Associated Binding Protein 2 (GAB2))

Autre désignation: GAB2

Sujet: This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.

Poids moléculaire: 74.5 kDa

ID gène: 9846

UniProt: Q9UQC2

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, BCR Signaling, L'effet Warburg