NGFR anticorps (FITC)

N° du produit ABIN7540431

L’anticorps Souris Monoclonal anti-NGFR a été validé pour FACS et ICFC. Il convient pour détecter NGFR dans des échantillons de Humain, Non-Human Primate, Lapin, Cat et Furet.

Aperçu rapide pour NGFR anticorps (FITC) (ABIN7540431)

Antigène: NGFR (Nerve Growth Factor Receptor (NGFR))

Reactivité: Humain, Non-Human Primate, Lapin, Cat, Furet

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NGFR est conjugé à/à la FITC

Application: Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)

Clone: NGFR5

Détail du produit anti-NGFR anticorps (FITC)

Fonction: Anti-Hu CD271 FITC

Specificité: The mouse monoclonal antibody NGFR5 (originally C34C) recognizes an epitope within ammino acids 1 - 160 of CD271/NGFR, a 75 kDa transmembrane glycoprotein of the TNFR superfamily.

Aucune reactivité croisée: Souris, Rat

Purification: Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: Purified CD271 protein isolated from human melanoma cell line A875

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. Extracellular and intracellular staining.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Détails sur NGFR

Antigène: NGFR (Nerve Growth Factor Receptor (NGFR))

Autre désignation: CD271

Sujet:

NCBI Full Gene Name: nerve growth factor receptor

Description: CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.

Other names: TNFRSF16, NGFR, p75NTR, p75NGFR

Gene name: NGFR

ID gène: 4804

UniProt: P08138

Pathways: Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding