Recombinant CD19 anticorps
Aperçu rapide pour Recombinant CD19 anticorps (ABIN7543176)
Antigène
Voir toutes CD19 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-CD19 [MB19-1], Mouse IgG1, kappa
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Specificité
- This antibody recognizes murine MB19-1 (CD19), a transmembrane protein present in B lymphocytes that regulates its activation. It is required for proper differentiation of B-1 cells.
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Réactivité croisée
- Chien
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Attributs du produit
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Original Species of Ab: Mouse
Original Format of Ab: IgA
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Purification
- Protein A affinity purified
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Immunogène
- This antibody was raised by immunising CD19-deficient mice with a cell line of mCD19+ mouse pre-B cells.
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Isotype
- IgG1 kappa
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Indications d'application
- This clone can be used to detect and analyze the presence of the CD19 transmembrane protein. The specificity towards the protein has been confirmed using ELISA and immunofluorescence (Sato et al., 1996, PMID: 8906812). Additionally, the MB19-1 antibody has been used in several flow cytometry assays. One group used this antibody to determine the differences in CD19 distribution between cells of young and old mice (Yamamoto et al., 2018, PMID: 29625072). Another group used it to differentiate eosinophils from other leukocytes (Vanella et al., 2017, PMID: 27043413). A final group used flow cytometry to determine the fraction of B cells cells in a sample with this antibody (Bedaret et al., 2009, PMID: 19907079).
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Commentaires
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This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgA format, for improved compatibility with existing reagents, assays and techniques.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD19 (CD19 Molecule (CD19))
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Autre désignation
- CD19
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Sujet
- B-lymphocyte antigen CD19, Differentiation antigen CD19, B-lymphocyte surface antigen B4, B4, CD19 Molecule, CD19 antigen
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UniProt
- P25918
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Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Antigène
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