CD19 anticorps (AA 485-556)

N° du produit ABIN724595

L’anticorps Lapin Polyclonal anti-CD19 a été validé pour FACS, ELISA, IHC (fro), IHC (p), IF (cc) et IF (p). Il convient pour détecter CD19 dans des échantillons de Humain, Souris, Rat et Mouton. Il y a 3+ publications disponibles.

Aperçu rapide pour CD19 anticorps (AA 485-556) (ABIN724595)

Highlights:

• High quality CD19 Anticorps primaire for the detection of CD19.
• Reliable product with high standard validation data

Antigène: CD19 (CD19 Molecule (CD19))

Reactivité: Humain, Souris, Rat, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD19 est non-conjugé

Application: Flow Cytometry (FACS), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-CD19 anticorps

Épitope: AA 485-556

Réactivité croisée: Humain, Souris, Rat, Mouton

Homologie: Cow,Pig,Horse,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from rat CD19

Isotype: IgG

Informations sur le produit:

What can the CD19 Antibody ABIN724595 be used for?: This polyclonal CD19 Antibody detects CD19. The CD19 Antibody has been validated for various applications and can be used for the detection of CD19 and derivatives by Flow Cytometry, ELISA, Immunohistochemistry (Frozen Sections), Immunohistochemistry (Paraffin-embedded Sections), Immunofluorescence (Cultured Cells), Immunofluorescence (Paraffin-embedded Sections).

What validation data is available for this CD19 Antibody?: The Anticorps primaire is referenced in 3 publications and is characterized by a proven, very high reliability. It has currently 4 product images that show its performance in a variety of applications. The product is currently available in 100 μL quantity. CD19 Antibody for the detection of CD19 and derivatives.

What is the function of CD19?: Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. [provided by RefSeq, Jul 2008].

Information d'application

Indications d'application: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-CD19 (ABIN724595)

Takahashi, Ikezumi, Saitoh: "Rituximab protects podocytes and exerts anti-proteinuric effects in rat adriamycin-induced nephropathy independent of B-lymphocytes." dans: Nephrology (Carlton, Vic.), Vol. 22, Issue 1, pp. 49-57, (2016) (PubMed).

Reese, Wilson, Huang, Redfield, Zhong, Djamali: "Calcineurin Inhibitor Minimization With Ixazomib, an Investigational Proteasome Inhibitor, for the Prevention of Antibody Mediated Rejection in a Preclinical Model." dans: Transplantation, (2015) (PubMed).

Goodwin, Choi, Hsieh, Neugent, Ahn, Hayenga, Singh, Shackelford, Lee, Shulaev, Dhar, Takeda, Kim: "Targeting Hypoxia-Inducible Factor-1α/Pyruvate Dehydrogenase Kinase 1 Axis by Dichloroacetate Suppresses Bleomycin-induced Pulmonary Fibrosis." dans: American journal of respiratory cell and molecular biology, Vol. 58, Issue 2, pp. 216-231 (PubMed).

Détails sur CD19

Antigène: CD19 (CD19 Molecule (CD19))

Autre désignation: CD19

Sujet:

Synonyms: AW495831, B-lymphocyte antigen CD19, Differentiation antigen CD19, CD19

Background: Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.

ID gène: 12478

UniProt: F1LNH2

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway