CD80 anticorps (Elab Fluor®Violet 610)

N° du produit ABIN7566682

Cet anticorps Hamster arménien Monoclonal détecte spécifiquement CD80 dans FACS. Il présente une réactivité envers Souris.

Aperçu rapide pour CD80 anticorps (Elab Fluor®Violet 610) (ABIN7566682)

Antigène: CD80

Reactivité: Souris

Hôte: Hamster arménien

Clonalité: Monoclonal

Conjugué: Cet anticorp CD80 est conjugé à/à la Elab Fluor®Violet 610

Application: Flow Cytometry (FACS)

Clone: 16-10A1

Détail du produit anti-CD80 anticorps (Elab Fluor®Violet 610)

Fonction: Elab Fluor®Violet 610 Anti-Mouse CD80 Antibody[16-10A1]

Isotype: IgG

Information d'application

Indications d'application: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10 cells in 100 μL volume].

Commentaires:

Matching Isotype Control: E-AB-F09853T

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Stock: 4 °C

Stockage commentaire: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Date de péremption: 12 months

Détails sur CD80

Antigène: CD80

Autre désignation: CD80

Sujet: Activation B7-1 antigen,B7,Cd80,T-lymphocyte activation antigen CD80,CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

ID gène: 12519

UniProt: Q00609

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints