CD86 anticorps (Elab Fluor®Violet 610)

N° du produit ABIN7566685

Cet anticorps Rat Monoclonal détecte spécifiquement CD86 dans FACS. Il présente une réactivité envers Souris.

Aperçu rapide pour CD86 anticorps (Elab Fluor®Violet 610) (ABIN7566685)

Antigène: CD86

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD86 est conjugé à/à la Elab Fluor®Violet 610

Application: Flow Cytometry (FACS)

Clone: GL-1

Détail du produit anti-CD86 anticorps (Elab Fluor®Violet 610)

Fonction: Elab Fluor®Violet 610 Anti-Mouse CD86 Antibody[GL-1]

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10 cells in 100 μL volume].

Commentaires:

Matching Isotype Control: E-AB-F09833T

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Stock: 4 °C

Stockage commentaire: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Date de péremption: 12 months

Détails sur CD86

Antigène: CD86

Autre désignation: CD86

Sujet: Activation B7-2 antigen,Cd86,ETC-1,Early T-cell costimulatory molecule 1,T-lymphocyte activation antigen CD86,CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

ID gène: 12524

UniProt: P42082

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation