CD47 anticorps (Elab Fluor®700)
Aperçu rapide pour CD47 anticorps (Elab Fluor®700) (ABIN7566749)
Antigène
Voir toutes CD47 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- Elab Fluor®700 Anti-Human CD47 Antibody[CC2C6D4]
-
Isotype
- IgG1, kappa
-
-
-
-
Indications d'application
- Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.
-
Commentaires
-
Matching Isotype Control: E-AB-F09792M1
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.
-
Stock
- 4 °C
-
Stockage commentaire
- This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
-
Date de péremption
- 12 months
-
-
- CD47
-
Autre désignation
- CD47
-
Sujet
- Cd47,IAP,Integrin-associated protein,Leukocyte surface antigen CD47,CD47 also known as Rh-associated protein, gp42, integrin-associated protein (IAP), and neurophilin, is a 42-52 kD member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. Two splice variants have been described in the cytoplasmic tail, the shorter form is expressed in bone-marrow-derived cells, endothelial cells, and fibroblasts while the longer form is expressed by neural tissues. CD47 expression is widely distributed in hematopoietic cells including thymocytes, T cells, B cells, monocytes, platelets, and erythrocytes as well as epithelial cells, endothelial cells, fibroblasts, and neural tissues. CD47 functions as an adhesion molecule and thrombospondin receptor and is non-covalently associated with β3 integrins CD51/CD61, CD41/CD61. Thrombospondin is a ligand for CD47, in the absence of CD47 mice show defects in host defense and β3 integrin-dependent ligand binding, migration, and cellular activation. CD47 is also part of the Rh complex on erythrocytes.
-
ID gène
- 961
-
UniProt
- Q08722
Antigène
-