Leptin anticorps (AA 22-167)

N° du produit ABIN7596041

Cet anticorps anti-Leptin est un anticorps Souris Monoclonal détectant Leptin dans WB, ELISA, ICC et IF. Adapté pour Humain.

Aperçu rapide pour Leptin anticorps (AA 22-167) (ABIN7596041)

Antigène: Leptin (LEP)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Leptin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: AT7E10

Détail du produit anti-Leptin anticorps

Épitope: AA 22-167

Fonction: Human Leptin/OB antibody

Purification: protein-A affinity chromatography

Immunogène: Recombinant human Leptin/OB (22-167aa) purified from E. coli.

Isotype: IgG2b kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Détails sur Leptin

Antigène: Leptin (LEP)

Autre désignation: Leptin/OB

Sujet: Human leptin is a 16- kDa nonglycosylated hormone that is produced in mature adipocytes. Leptin acts primarilyin the hypothalamus to reduce food intake and body weight. In ob/ob mice, the gene encoding leptin is mutated,resulting in morbid obesity and associated abnormalities, including hyperphagia, hypothermia, diabetes andinfertility. The function of leptin in regulating appetite and metabolism, as well as the possibility of usingleptin as a therapeutic agent, are currently under intense investigation.

NCBI Accession: NP_000221

Pathways: Signalistation JAK/STAT, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process