FASL anticorps (AA 196-281)

N° du produit ABIN726410

Détail du produit anti-FASL anticorps

Antigène: FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

Épitope: AA 196-281

Reactivité: Humain, Souris, Rat, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FASL est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Porc, Rat

Homologie: Cow

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Fas Ligand

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-FASL (ABIN726410)

Lv, Zheng, Zhou, Jia, Wang, Liu, Zhao, Ji, Li, Cao: "Antiproliferative and Apoptosis-inducing Effect of exo-Protoporphyrin IX based Sonodynamic Therapy on Human Oral Squamous Cell Carcinoma." dans: Scientific reports, Vol. 7, pp. 40967, (2017) (PubMed).

Wang, Zhang, Yang, Luo, Zhang, Wang: "Lipopolysaccharide-induced expression of FAS ligand in cultured immature boar sertoli cells through the regulation of pro-inflammatory cytokines and miR-187." dans: Molecular reproduction and development, (2015) (PubMed).

Song, Li, Shi, Lehmler, Fu, Su, Xia, Song, Song: "Polychlorinated Biphenyl Quinone Metabolite Promotes p53-Dependent DNA Damage Checkpoint Activation, S-Phase Cycle Arrest and Extrinsic Apoptosis in Human Liver Hepatocellular Carcinoma HepG2 Cells." dans: Chemical research in toxicology, Vol. 28, Issue 11, pp. 2160-9, (2015) (PubMed).

Peng, Fu, Guo, Zhang, Di, Jiang, Li: "Effects and Mechanism of Baicalin on Apoptosis of Cervical Cancer HeLa Cells I n -v itro." dans: Iranian journal of pharmaceutical research : IJPR, Vol. 14, Issue 1, pp. 251-61, (2015) (PubMed).

Qi, Fu, Wang, Liu, Quan, Kourouma, Yan, Yu, Duan, Yang: "BPA-induced apoptosis of rat Sertoli cells through Fas/FasL and JNKs/p38 MAPK pathways." dans: Reproductive toxicology (Elmsford, N.Y.), Vol. 50, pp. 108-16, (2014) (PubMed).

Chen, Xie, Xue, Ji, Chang, Ma, Bi: "Characterization of cytotoxicity-related gene expression in response to virulent Marek's disease virus infection in the bursa of Fabricius." dans: Research in veterinary science, Vol. 94, Issue 3, pp. 496-503, (2013) (PubMed).

Shi, Song, Wang, Wang, Liang, Hu, Yu, Guan, Cheng, Yang: "β-Benzene hexachloride induces apoptosis of rat Sertoli cells through generation of reactive oxygen species and activation of JNKs and FasL." dans: Environmental toxicology, Vol. 26, Issue 2, pp. 124-35, (2011) (PubMed).

Shi, Song, Wang, Liang, Hu, Guan, Cheng, Yang: "p,p'-DDE induces apoptosis of rat Sertoli cells via a FasL-dependent pathway." dans: Journal of biomedicine & biotechnology, Vol. 2009, pp. 181282, (2009) (PubMed).

Détails sur FASL

Antigène: FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))

Autre désignation: Fas Ligand (FASL Produits)

Synonymes: anticorps ALPS1B, anticorps APT1LG1, anticorps APTL, anticorps CD178, anticorps CD95-L, anticorps CD95L, anticorps FASL, anticorps TNFSF6, anticorps fasl, anticorps Fas-L, anticorps Faslg, anticorps Tnfsf6, anticorps gld, anticorps Apt1Lg1, anticorps Fasl, anticorps FASLG, anticorps zgc:162027, anticorps Fas ligand, anticorps Fas ligand L homeolog, anticorps Fas ligand (TNF superfamily, member 6), anticorps FASLG, anticorps faslg.L, anticorps Fasl, anticorps Faslg, anticorps faslg

Sujet:

Synonyms: APTL, FASL, CD178, CD95L, ALPS1B, CD95-L, TNFSF6, APT1LG1, Tumor necrosis factor ligand superfamily member 6, Apoptosis antigen ligand, CD95 ligand, Fas antigen ligand, Fas ligand, FASLG

Background: Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. The FasL intracellular domain (FasL ICD) cytoplasmic form induces gene transcription inhibition.

ID gène: 356

UniProt: P48023

Pathways: Apoptose, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity