ETFA anticorps (AA 1-333)

N° du produit ABIN7599281

L’anticorps Lapin Polyclonal anti-ETFA a été validé pour WB, IHC, ELISA, IF, ICC et FACS. Il convient pour détecter ETFA dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ETFA anticorps (AA 1-333) (ABIN7599281)

Antigène: ETFA (Electron-Transfer-Flavoprotein, alpha Polypeptide (ETFA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ETFA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Détail du produit anti-ETFA anticorps

Épitope: AA 1-333

Fonction: Anti-ETFA Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-ETFA Antibody Picoband® (ABIN7599281). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human ETFA recombinant protein (Position: M1-K333).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Barton, D. E., Yang-Feng, T. L., Finocchiaro, G., Ozasa, H., Tanaka, K., Francke, U. Short chain acyl-CoA dehydrogenase (ACADS) maps to chromosome 12 (q22-qter) and electron transfer flavoprotein (ETFA) to 15 (q23-q25). (Abstract) Cytogenet. Cell Genet. 46: 577-578, 1987. 2. Finocchiaro, G., Ikeda, Y., Barton, D., Francke, U., Tanaka, K. Molecular cloning and gene mapping of alpha-subunit of human electron transfer flavoprotein. (Abstract) Am. J. Hum. Genet. 41: A214, 1987. 3. Finocchiaro, G., Ito, M., Ikeda, Y., Tanaka, K. Molecular cloning and nucleotide sequence of cDNAs encoding the alpha-subunit of human electron transfer flavoprotein. J. Biol. Chem. 263: 15773-15780, 1988.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur ETFA

Antigène: ETFA (Electron-Transfer-Flavoprotein, alpha Polypeptide (ETFA))

Autre désignation: ETFA

Sujet:

Synonyms: Phosphopantothenate--cysteine ligase, Phosphopantothenoylcysteine synthetase, PPC synthetase, PPCS, COAB

Tissue Specificity: Expressed in heart, placenta, skeletal muscle kidney, pancreas, spleen, prostate, testis, ovary, ileum and colon. Expressed in lung endothelial and smooth muscle cells (at protein level).

Background: The human ETFA gene encodes the Electron-transfer-flavoprotein, alpha subunit, also known as ETF-α. Together with Electron-transfer-flavoprotein, beta subunit, encoded by the 'ETFB' gene, it forms the heterodimericElectron transfer flavoprotein (ETF). ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 35 kDa

ID gène: 2108

UniProt: P13804

Pathways: SARS-CoV-2 Protein Interactome