Rab4 anticorps (AA 110-216)

N° du produit ABIN7599733

Cet anticorps Lapin Polyclonal détecte spécifiquement Rab4 dans WB, IHC et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Rab4 anticorps (AA 110-216) (ABIN7599733)

Antigène: Rab4 (RAB4A) (RAB4A, Member RAS Oncogene Family (RAB4A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Rab4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Rab4 anticorps

Épitope: AA 110-216

Fonction: Anti-Rab4/RAB4A Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Rab4/RAB4A Antibody Picoband® (ABIN7599733). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Rab4/RAB4A recombinant protein (Position: D110-C216).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Barbosa, M. D. F. S., Johnson, S. A., Achey, K., Gutierrez, M., Wakeland, E. K., Zerial, M., Kingsmore, S. F. The Rab protein family: genetic mapping of six Rab genes in the mouse. Genomics 30: 439-444, 1995. 2. Bielli, A., Thornqvist, P.-O., Hendrick, A. G., Finn, R., Fitzgerald, K., McCaffrey, M. W. The small GTPase Rab4A interacts with the central region of cytoplasmic dynein light intermediate chain-1. Biochem. Biophys. Res. Commun. 281: 1141-1153, 2001. 3. Goueli, B. S., Powell, M. B., Finger, E. C., Pfeffer, S. R. TBC1D16 is a Rab4A GTPase activating protein that regulates receptor recycling and EGF receptor signaling. Proc. Nat. Acad. Sci. 109: 15787-15792, 2012.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur Rab4

Antigène: Rab4 (RAB4A) (RAB4A, Member RAS Oncogene Family (RAB4A))

Autre désignation: RAB4A

Sujet:

Synonyms: Solute carrier family 12 member 5, Electroneutral potassium-chloride cotransporter 2, K-Cl cotransporter 2, hKCC2, Neuronal K-Cl cotransporter, SLC12A5, KCC2, KIAA1176

Tissue Specificity: Brain specific. Detected in neuronal cells.

Background: This gene is a member of the largest group in the Ras superfamily of small GTPases, which regulate membrane trafficking. The encoded protein is associated with early endosomes and is involved in their sorting and recycling. The protein also plays a role in regulating the recycling of receptors from endosomes to the plasma membrane. Alternatively spliced transcript variants have been observed for this gene.

Poids moléculaire: 24 kDa

ID gène: 5867

UniProt: P20338