SLBP anticorps (AA 146-270)

N° du produit ABIN7600074

L’anticorps Lapin Polyclonal anti-SLBP a été validé pour WB, ELISA, IHC, IF, ICC et FACS. Il convient pour détecter SLBP dans des échantillons de Humain et Souris.

Aperçu rapide pour SLBP anticorps (AA 146-270) (ABIN7600074)

Antigène: SLBP (Stem-Loop Binding Protein (SLBP))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLBP est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Détail du produit anti-SLBP anticorps

Épitope: AA 146-270

Fonction: Anti-SLBP Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-SLBP Antibody Picoband® (ABIN7600074). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SLBP recombinant protein (Position: K146-S270).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Martin, F., Schaller, A., Eglite, S., Schumperli, D., Muller, B. The gene for histone RNA hairpin binding protein is located on human chromosome 4 and encodes a novel type of RNA binding protein. EMBO J. 16: 769-778, 1997. 2. Tan, D., Marzluff, W. F., Dominski, Z., Tong, L. Structure of histone mRNA stem-loop, human stem-loop binding protein, and 3-prime-hExo ternary complex. Science 339: 318-321, 2013. 3. Wang, Z.-F., Whitfield, M. L., Ingledue, T. C., III, Dominski, Z., Marzluff, W. F. The protein that binds the 3-prime end of histone mRNA: a novel RNA-binding protein required for histone pre-mRNA processing. Genes Dev. 10: 3028-3040, 1996.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur SLBP

Antigène: SLBP (Stem-Loop Binding Protein (SLBP))

Autre désignation: SLBP

Sujet:

Synonyms: Histone RNA hairpin-binding protein, Histone stem-loop-binding protein, SLBP, HBP

Tissue Specificity: Widely expressed.

Background: Histone RNA hairpin-binding protein is a protein that in human is encoded by the SLBP gene. This gene is mapped to 4p16.3. This gene encodes a protein that binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.

Poids moléculaire: 40 kDa

ID gène: 7884

UniProt: Q14493