NDFIP2 anticorps (AA 16-336)
Aperçu rapide pour NDFIP2 anticorps (AA 16-336) (ABIN7600175)
Antigène
Voir toutes NDFIP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 16-336
-
Fonction
- Anti-NDFIP2 Antibody
-
Réactivité croisée (Details)
- No cross-reactivity with other proteins.
-
Attributs du produit
- Anti-NDFIP2 Antibody (ABIN7600175). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
-
Purification
- Immunogen affinity purified.
-
Immunogène
- E.coli-derived human NDFIP2 recombinant protein (Position: M16-L336).
-
Isotype
- IgG
-
-
-
-
Indications d'application
-
Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
Concentration
- 500 μg/mL
-
Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))
-
Autre désignation
- NDFIP2
-
Sujet
-
Synonyms: Disintegrin and metalloproteinase domain-containing protein 2,ADAM 2,Cancer/testis antigen 15,CT15,Fertilin subunit beta,PH-30,PH30,PH30-beta,ADAM2,FTNB,
Tissue Specificity: Expressed specifically in spermatogenic cells in the seminiferous cells. Not detected in fetal tissues.
Background: NEDD4 family-interacting protein 2 is a protein that in humans is encoded by the NDFIP2 gene. The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.
-
Poids moléculaire
- 39 kDa
-
ID gène
- 54602
-
Pathways
- Negative Regulation of Transporter Activity, SARS-CoV-2 Protein Interactome
Antigène
-