FGF3 anticorps (AA 18-239)

N° du produit ABIN7600325

Cet anticorps anti-FGF3 est un anticorps Lapin Polyclonal détectant FGF3 dans IHC et ELISA. Adapté pour Humain.

Aperçu rapide pour FGF3 anticorps (AA 18-239) (ABIN7600325)

Antigène: FGF3 (Fibroblast Growth Factor 3 (FGF3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGF3 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-FGF3 anticorps

Épitope: AA 18-239

Fonction: Anti-FGF3 Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-FGF3 Antibody Picoband® (ABIN7600325). Tested in ELISA, IHC applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human FGF3 recombinant protein (Position: A18-H239).

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Alsmadi, O., Meyer, B. F., Alkuraya, F, Wakil, S., Alkayal, F., Al-Saud, H., Ramzan, K., Al-Sayed, M. Syndromic congenital sensorineural deafness, microtia and microdontia resulting from a novel homoallelic mutation in fibroblast growth factor 3 (FGF3). Europ. J. Hum. Genet. 17: 14-21, 2009. 2. Brookes, S., Smith, R., Casey, G., Dickson, C., Peters, G. Sequence organization of the human int-2 gene and its expression in teratocarcinoma cells. Oncogene 4: 429-436, 1989. 3. Casey, G., Smith, R., McGillivray, D., Peters, G., Dickson, C. Characterization and chromosome assignment of the human homolog of int-2, a potential proto-oncogene. Molec. Cell. Biol. 6: 502-510, 1986.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur FGF3

Antigène: FGF3 (Fibroblast Growth Factor 3 (FGF3))

Autre désignation: FGF3

Sujet:

Synonyms: Glutathione S-transferase Mu 3, GST class-mu 3, GSTM3-3, hGSTM3-3, GSTM3, GST5,

Tissue Specificity: Testis and brain.

Background: INT-2 proto-oncogene protein also known as FGF-3 is a protein that in humans is encoded by the FGF3 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation.

Poids moléculaire: 33 kDa

ID gène: 2248

UniProt: P11487

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway